GLP-1 raw material · research use · factory-direct
Retatrutide raw material supplier CAS 2381089-83-2 · Triple GIP / GLP-1 / glucagon receptor agonist
Retatrutide raw material from Pepti, Guangzhou: a triple GIP, GLP-1 and glucagon receptor agonist supplied as bulk powder or lyophilized vials, released with a batch COA reporting RP-HPLC purity and MS identity. Nine public records are in the Pepti COA library (98.72% to 99.55% by HPLC), and an independent Janoshik report on one Pepti retatrutide sample is verifiable at the laboratory. Sample 1 kit (10 vials); OEM from 50 kits.
What Retatrutide is
Triple agonist of the GIP, GLP-1 and glucagon receptors (39 residues, C20 diacid acylation). INN retatrutide; published in WHO INN lists.
Retatrutide is a 39-residue synthetic peptide designed to activate three receptors: GIP, GLP-1 and glucagon. Like tirzepatide it is built on a GIP-like backbone with non-natural residues that resist enzymatic cleavage, and it carries a C20 fatty diacid on a lysine side chain through a γ-glutamate and polyethylene-glycol spacer. The combination of a long lipid chain and a sequence that borrows from glucagon makes it one of the more hydrophobic molecules on this site, with chromatographic behaviour closer to tirzepatide than to semaglutide.
The sequence is public through the WHO INN records, and NCATS GSRS lists the substance under UNII NOP2Y096GV with the full 39-residue sequence. PubChem CID 171934787 carries the free-peptide formula C221H342N46O68 and a computed molecular weight of about 4731 g/mol. One identifier note for buyers doing their own cross-check: the CAS number 2381089-83-2, as printed on Pepti's product documentation, was not yet listed as a PubChem synonym on the review date, so a CAS search in PubChem may return nothing; search by name or by the CID instead, or use the GSRS record.
Retatrutide is also the compound for which Pepti has an independent, publicly verifiable data point. Janoshik Analytical report #210105 identifies peptioem.com as client and manufacturer for a Retatrutide 20 mg sample and reports 19.52 mg content and 99.837% purity, analyzed 2026-10-07. The report can be checked at verify.janoshik.com. It is a sample-specific result for one submitted vial and is not a claim about every retatrutide lot; it does show the content-versus-purity distinction that the COA reading guide explains.
Supply formats, units and minimums
Two formats, one unit system, no hidden tiers.
Raw powder
Retatrutide raw material is supplied as bulk powder from 5 g, shipped cold-chain. Each shipment is tied to one production batch and its COA; the lot code on the container matches the lot code on the certificate. Raw powder is the format research organizations and fill-finish partners ask for when they run their own weighing, reconstitution or formulation work.
Lyophilized vials
The same batch can be filled as lyophilized powder in glass vials. The unit is fixed: 1 kit = 10 vials. Published lot strengths for Retatrutide are 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 100 mg; other fill weights are quoted on request. Vials ship with a neutral label by default; private-label artwork is handled under the OEM minimum.
Minimums
- Sample order: 1 kit (10 vials) of one compound and strength, so a buyer can test before scaling.
- Private-label OEM: 50 kits (500 vials) per artwork, after label scope is approved.
- Bulk powder: from 5 g, shipped cold-chain.
- Custom sequences: 100 kits (1,000 vials), typically about 15 days after specification and payment confirmation — for analogues not listed on this site.
Retatrutide public records cover vial strengths from 5 mg to 100 mg, the same ladder as tirzepatide, and the two compounds are often ordered together by the same laboratories and distributors. Because the lipidated impurity classes are similar for both, a buyer who has already validated an HPLC method for tirzepatide can usually adapt it for retatrutide with gradient changes only; Pepti can share the release chromatogram for a lot to help with that.
Specification and batch evidence
Published batch range: 98.72%–99.55% by HPLC across 9 public records.
Every Retatrutide batch is released against a certificate of analysis that reports chromatographic purity (RP-HPLC, area-percent of the main peak) and molecular-weight identity (mass spectrometry, observed mass compared with the theoretical mass of C221H342N46O68). The COA also carries the lot code, manufacture date, test date and retest date. Those are the fields a buyer should match against the quoted lot before paying; nothing on this page replaces that lot-specific document.
What the certificate does not show matters just as much. HPLC area-percent describes how much of the UV-absorbing material elutes as the main peak; it does not quantify water, counter-ion, residual solvent or fill weight. MS identity confirms that the main component has the expected mass; it does not by itself prove the absence of a co-eluting isomer. Buyers who need those answers run their own panel on a received sample, and Pepti supports that route — see quality and batch records.
Public batch records for Retatrutide
- Record ↗
PEP260706-RT5
5 mg vial · HPLC 98.72% · tested 2026-07-15 - Record ↗
PEP260712-RT10
10 mg vial · HPLC 99.25% · tested 2026-07-21 - Record ↗
PEP260707-RT15
15 mg vial · HPLC 99.12% · tested 2026-07-15 - Record ↗
PEP260819-RT20
20 mg vial · HPLC 99.26% · tested 2026-08-22 - Record ↗
PEP260716-RT30
30 mg vial · HPLC 99.12% · tested 2026-07-29 - Record ↗
PEP260702-RT40
40 mg vial · HPLC 99.16% · tested 2026-07-15 - Record ↗
PEP260724-RT50
50 mg vial · HPLC 98.72% · tested 2026-07-29 - Record ↗
PEP260706-RT60
60 mg vial · HPLC 99.53% · tested 2026-07-15 - Record ↗
PEP260728-RT100
100 mg vial · HPLC 99.55% · tested 2026-08-03
Records mirrored from the public library on 2026-10-19; the linked page on peptioem.com is the authoritative copy and carries the PDF.
Lead-time ladder for the GLP-1 family
Three windows, counted from specification and payment confirmation.
- Sample kits5–10 days
typically, for 1-kit sample orders of a listed GLP-1 compound
- Production batch14–21 days
typically, for a first production batch after specification is confirmed
- OEM repeat order21–28 days
typically, for private-label repeat batches with artwork already approved
Lead times are typical ranges, not commitments; the applicable window is confirmed on each RFQ.
Retatrutide sits in the GLP-1 family ladder with the other five compounds on this site. A sample kit normally leaves the Guangzhou site within the first window because it is filled from a released batch. A first production batch takes the middle window because synthesis, cleavage, purification, lyophilization and QC run in sequence for your specification. OEM repeat orders take the longest window because label printing, carton proofing and fill are added after the material is released. If a batch is already in stock, the quote says so and the window shortens; if a custom strength or analogue is requested, the quote says that too.
How to verify Retatrutide from Pepti before you pay
Four checks that take less time than a wire transfer.
- Open the public record. Pick a lot from the list above and open it on peptioem.com. Compare the compound, strength, lot alias, purity result and dates with the quote you received.
- Ask for the lot that will ship. Public records are examples of the document format. For your order, request the COA of the exact lot allocated to you and confirm the lot code again on the shipping label when it arrives.
- Check the identifiers. CAS 2381089-83-2 and the theoretical mass of C221H342N46O68 are public; the MS result on the COA should sit within normal instrument tolerance of that mass.
- Test a received sample if your QA requires it. Order 1 kit (10 vials), send one vial to a laboratory of your choice, and compare. Pepti's own independent data point is Janoshik report #210105 (Retatrutide 20 mg sample: 19.52 mg content, 99.837% purity, analyzed 2026-10-07), which is sample-specific and verifiable at verify.janoshik.com.
Storage, shipping and handling
Cold chain in transit; retest date on the COA.
Retatrutide ships from Guangzhou as sealed lyophilized powder inside an insulated carton with cold packs or dry ice depending on route and season. On arrival, match the lot alias across courier label, inner carton and certificate, inspect the cold packs and the container seals, and log the lot before it goes into storage. Dispatch photographs by month and destination are on the order-photos page.
Keep sealed containers cold, dry and dark under the conditions on the batch certificate, and equilibrate to room temperature before opening. Retatrutide's long lipid chain makes the lyophilized powder somewhat waxy in appearance compared with non-acylated peptides; that is normal and not a sign of moisture uptake. Aliquot bulk powder once rather than reopening the primary container, and label every aliquot with the lot alias.
Use the retest date on the certificate as the trigger for a re-examination by HPLC and MS. Compare the re-test against the certificate values and the published range for the compound, allowing for method differences in the area-percent. For a re-test that disagrees materially with the certificate, contact Pepti with the lot alias, the chromatogram and the spectrum; the Janoshik route shows what an independent laboratory report for this compound looks like.
Research-use boundary
Other GLP-1-family compounds from the same site
Semaglutide
GLP-1 receptor agonist · CAS 910463-68-2
Tirzepatide
Dual GIP / GLP-1 receptor agonist · CAS 2023788-19-2
Cagrilintide
Long-acting amylin analogue · CAS 1415456-99-3
Mazdutide
Dual GLP-1 / glucagon receptor agonist · CAS 2259884-03-0
Survodutide
Dual glucagon / GLP-1 receptor agonist · CAS 2805997-46-8
Questions buyers ask
Does the Janoshik report cover the retatrutide lot I will receive?
No. Report #210105 covers one submitted Retatrutide 20 mg sample (19.52 mg content, 99.837% purity, analyzed 2026-10-07) and is verifiable at verify.janoshik.com. Your order ships with Pepti's batch certificate for the lot allocated to you; if your QA needs an independent result for that lot, order 1 kit (10 vials) and send a vial to a laboratory of your choice.
Why does a PubChem CAS search for retatrutide return nothing?
Because CAS 2381089-83-2 was not listed as a PubChem synonym on the review date. The PubChem compound record (CID 171934787) exists under the name and carries the formula C221H342N46O68 and a computed molecular weight of about 4731 g/mol; NCATS GSRS lists retatrutide under UNII NOP2Y096GV with the sequence. Use any of those identifiers for your cross-check.
What are the minimums and lead times for retatrutide?
Sample order 1 kit (10 vials); bulk raw powder from 5 g, shipped cold-chain; private-label OEM from 50 kits (500 vials). Typical GLP-1-family lead times are 5–10 days for sample kits, 14–21 days for a production batch and 21–28 days for OEM repeat orders, confirmed on each quote.
What is retatrutide from Pepti intended for?
Research use by research organizations, laboratories and B2B buyers. For research use only. Not for human or veterinary use. Pepti does not present itself as a cGMP drug-substance (API) manufacturer or CDMO and does not publish a GMP certificate or DMF.
Request a quote for Retatrutide raw material
Send the compound, format (raw powder or lyophilized vials), quantity and destination. Mike at Pepti Supply replies on WhatsApp with the applicable batch record, lead-time window and unit pricing; email works too: contact@peptioem.com.