GLP-1 raw material · research use · factory-direct
Tirzepatide raw material supplier CAS 2023788-19-2 · Dual GIP / GLP-1 receptor agonist
Tirzepatide raw material from Pepti, Guangzhou: a dual GIP and GLP-1 receptor agonist supplied as bulk powder or lyophilized vials, released with a batch COA reporting RP-HPLC purity and MS identity. Nine public batch records are in the Pepti COA library, with HPLC results between 98.4% and 99.7% across vial strengths from 5 mg to 100 mg. Sample 1 kit (10 vials); OEM from 50 kits.
What Tirzepatide is
Dual GIP and GLP-1 receptor agonist (39 residues, C20 diacid acylation). INN tirzepatide; published in WHO INN lists.
Tirzepatide is a 39-residue synthetic peptide built on the GIP backbone and engineered to activate both the GIP receptor and the GLP-1 receptor. It carries two α-aminoisobutyric acid residues, at positions 2 and 13, that protect it from enzymatic cleavage, and a C20 fatty diacid attached to the lysine at position 20 through a γ-glutamate and two short polyethylene-glycol spacers. The C20 diacid is longer than the C18 chain on semaglutide, which makes tirzepatide more hydrophobic on a reversed-phase column and widens the gap between the main peak and non-acylated impurities, while narrowing the gap to acylation variants.
The sequence and modifications are public through the WHO INN records and PubChem CID 166567236, which lists the molecular formula C225H348N48O68 and a computed molecular weight of about 4813 g/mol. NCATS GSRS records the substance under UNII OYN3CCI6QE. Pepti produces tirzepatide by solid-phase synthesis of the protected backbone, on-resin or solution-phase acylation of the lysine side chain depending on the batch route, cleavage, preparative reversed-phase purification and lyophilization. Each batch certificate compares the observed mass from electrospray mass spectrometry with the theoretical value from that formula.
Because tirzepatide is heavily lipidated, its chromatography is sensitive to method conditions: column temperature, gradient slope and the acid modifier all change where the lipidated variants elute relative to the main peak. A buyer re-testing a Pepti lot in their own laboratory should expect the purity figure to move slightly with method, and should compare chromatogram shape, not just the area-percent, before concluding anything about the lot. The HPLC versus MS guide covers this in detail.
Supply formats, units and minimums
Two formats, one unit system, no hidden tiers.
Raw powder
Tirzepatide raw material is supplied as bulk powder from 5 g, shipped cold-chain. Each shipment is tied to one production batch and its COA; the lot code on the container matches the lot code on the certificate. Raw powder is the format research organizations and fill-finish partners ask for when they run their own weighing, reconstitution or formulation work.
Lyophilized vials
The same batch can be filled as lyophilized powder in glass vials. The unit is fixed: 1 kit = 10 vials. Published lot strengths for Tirzepatide are 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 100 mg; other fill weights are quoted on request. Vials ship with a neutral label by default; private-label artwork is handled under the OEM minimum.
Minimums
- Sample order: 1 kit (10 vials) of one compound and strength, so a buyer can test before scaling.
- Private-label OEM: 50 kits (500 vials) per artwork, after label scope is approved.
- Bulk powder: from 5 g, shipped cold-chain.
- Custom sequences: 100 kits (1,000 vials), typically about 15 days after specification and payment confirmation — for analogues not listed on this site.
Tirzepatide has the broadest public strength ladder on this site, 5 mg to 100 mg per vial, because the same bulk lot is filled for laboratory sample work at the low end and for distributor stock at the high end. A 100 mg vial and a 5 mg vial from the same lot share one certificate; what differs is the fill record. If you need a strength outside the published ladder, or raw powder in a quantity above the 5 g minimum, state it on the RFQ and the quote will say whether it comes from released stock or a new batch.
Specification and batch evidence
Published batch range: 98.4%–99.7% by HPLC across 9 public records.
Every Tirzepatide batch is released against a certificate of analysis that reports chromatographic purity (RP-HPLC, area-percent of the main peak) and molecular-weight identity (mass spectrometry, observed mass compared with the theoretical mass of C225H348N48O68). The COA also carries the lot code, manufacture date, test date and retest date. Those are the fields a buyer should match against the quoted lot before paying; nothing on this page replaces that lot-specific document.
What the certificate does not show matters just as much. HPLC area-percent describes how much of the UV-absorbing material elutes as the main peak; it does not quantify water, counter-ion, residual solvent or fill weight. MS identity confirms that the main component has the expected mass; it does not by itself prove the absence of a co-eluting isomer. Buyers who need those answers run their own panel on a received sample, and Pepti supports that route — see quality and batch records.
Public batch records for Tirzepatide
- Record ↗
PEP260718-TR5
5 mg vial · HPLC 98.5% · tested 2026-07-25 - Record ↗
PEP260706-TR10
10 mg vial · HPLC 99.6% · tested 2026-07-15 - Record ↗
PEP260722-TR15
15 mg vial · HPLC 98.4% · tested 2026-07-29 - Record ↗
PEP260723-TR20
20 mg vial · HPLC 99.2% · tested 2026-07-29 - Record ↗
PEP260722-TR30
30 mg vial · HPLC 99.7% · tested 2026-07-29 - Record ↗
PEP260722-TR40
40 mg vial · HPLC 99.2% · tested 2026-07-29 - Record ↗
PEP260716-TR50
50 mg vial · HPLC 99.5% · tested 2026-07-22 - Record ↗
PEP260713-TR60
60 mg vial · HPLC 99.5% · tested 2026-07-22 - Record ↗
PEP260723-TR100
100 mg vial · HPLC 98.9% · tested 2026-07-29
Records mirrored from the public library on 2026-10-19; the linked page on peptioem.com is the authoritative copy and carries the PDF.
Lead-time ladder for the GLP-1 family
Three windows, counted from specification and payment confirmation.
- Sample kits5–10 days
typically, for 1-kit sample orders of a listed GLP-1 compound
- Production batch14–21 days
typically, for a first production batch after specification is confirmed
- OEM repeat order21–28 days
typically, for private-label repeat batches with artwork already approved
Lead times are typical ranges, not commitments; the applicable window is confirmed on each RFQ.
Tirzepatide sits in the GLP-1 family ladder with the other five compounds on this site. A sample kit normally leaves the Guangzhou site within the first window because it is filled from a released batch. A first production batch takes the middle window because synthesis, cleavage, purification, lyophilization and QC run in sequence for your specification. OEM repeat orders take the longest window because label printing, carton proofing and fill are added after the material is released. If a batch is already in stock, the quote says so and the window shortens; if a custom strength or analogue is requested, the quote says that too.
How to verify Tirzepatide from Pepti before you pay
Four checks that take less time than a wire transfer.
- Open the public record. Pick a lot from the list above and open it on peptioem.com. Compare the compound, strength, lot alias, purity result and dates with the quote you received.
- Ask for the lot that will ship. Public records are examples of the document format. For your order, request the COA of the exact lot allocated to you and confirm the lot code again on the shipping label when it arrives.
- Check the identifiers. CAS 2023788-19-2 and the theoretical mass of C225H348N48O68 are public; the MS result on the COA should sit within normal instrument tolerance of that mass.
- Test a received sample if your QA requires it. Order 1 kit (10 vials), send one vial to a laboratory of your choice, and compare. Pepti's own independent data point is Janoshik report #210105 (Retatrutide 20 mg sample: 19.52 mg content, 99.837% purity, analyzed 2026-10-07), which is sample-specific and verifiable at verify.janoshik.com.
Storage, shipping and handling
Cold chain in transit; retest date on the COA.
Tirzepatide leaves Guangzhou as lyophilized powder in sealed containers, packed in an insulated carton with cold packs or dry ice by route. Check three things when the parcel arrives: the lot alias on the courier label and inner carton against the certificate, the condition of the cold packs, and the integrity of the container seals. Real dispatch photographs by month and destination are on the order-photos page, with recipient details blurred.
Store sealed containers cold, dry and protected from light, under the conditions stated on the batch certificate. Allow a container to equilibrate to room temperature before opening to prevent condensation on a hygroscopic powder. For bulk raw powder, aliquot once into working containers rather than reopening the primary container, and record the lot alias on every aliquot.
The certificate's retest date is a re-examination trigger. As it approaches, run HPLC and MS on a retained portion and compare with the certificate values. Tirzepatide's lipidated impurities elute close to the main peak, so a re-test on a different method may show a slightly different area-percent; compare the chromatogram shape with the one Pepti can provide for the lot before drawing conclusions. If a result falls well outside the published range, contact Pepti with the lot alias and your data.
Research-use boundary
Other GLP-1-family compounds from the same site
Semaglutide
GLP-1 receptor agonist · CAS 910463-68-2
Retatrutide
Triple GIP / GLP-1 / glucagon receptor agonist · CAS 2381089-83-2
Cagrilintide
Long-acting amylin analogue · CAS 1415456-99-3
Mazdutide
Dual GLP-1 / glucagon receptor agonist · CAS 2259884-03-0
Survodutide
Dual glucagon / GLP-1 receptor agonist · CAS 2805997-46-8
Questions buyers ask
Do all nine public tirzepatide records come from different lots?
Each public record is one lot-strength combination with its own lot alias, manufacture date and test date. They show the document format and the spread of results (98.4% to 99.7% by HPLC) across the published strengths. Your order ships with the certificate for the specific lot allocated to it, which you should request on the quote.
Can I order tirzepatide as raw powder rather than vials?
Yes. Bulk raw powder is supplied from 5 g and ships cold-chain, tied to one batch COA. Lyophilized vials use the unit 1 kit = 10 vials; a sample order is 1 kit, and private-label OEM starts at 50 kits (500 vials). Lead times are typically 5–10 days for sample kits, 14–21 days for a production batch and 21–28 days for OEM repeat orders.
How should I compare my own HPLC result with the Pepti certificate?
Compare chromatogram shape and the position of the main peak as well as the area-percent, because tirzepatide's lipidated impurities move with method conditions. Ask Pepti for the chromatogram and MS spectrum of your lot so your laboratory can match the method. The identity check is method-independent: the observed mass should agree with the theoretical mass for C225H348N48O68, about 4813 g/mol.
Is tirzepatide from Pepti suitable for drug-substance use?
No. It is a research-use raw material for research organizations, laboratories and B2B buyers. Pepti does not present itself as a cGMP drug-substance (API) manufacturer or CDMO and does not publish a GMP certificate or DMF. For research use only. Not for human or veterinary use.
Request a quote for Tirzepatide raw material
Send the compound, format (raw powder or lyophilized vials), quantity and destination. Mike at Pepti Supply replies on WhatsApp with the applicable batch record, lead-time window and unit pricing; email works too: contact@peptioem.com.